249 Optimized low pH niacinamide formulations show a significant induction of autophagy gene expression over neutral niacinamide control formula
نویسندگان
چکیده
منابع مشابه
Niacinamide Monograph
Introduction Niacinamide, also known as nicotinamide, is a water-soluble amide of nicotinic acid. Niacinamide is one of two principal forms of the B-complex vitamin, B3. Niacin was first isolated from rice bran in 1911. Niacinamide, the amide of niacin, was later isolated in 1934 by Warburg and Christian when coenzyme II, NADP, was extracted from horse erythrocytes. While niacinamide and niacin...
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Thirty schizophrenic alcoholics were included in a 100-patient clinical series testing a biochemical approach to the treatment of schizophrenia at the North Nassau Mental Health Center. Dr. David Raymond Hawkins, the Center's Director, reports that 25 of the 30 alcoholics are currently sober and that, 24 have either recovered from their schizophrenia or their symptoms of those 25, have abated. ...
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in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...
15 صفحه اولA randomized, double-blind, placebo-controlled trial of niacinamide for reduction of phosphorus in hemodialysis patients.
BACKGROUND AND OBJECTIVES Niacinamide inhibits intestinal sodium/phosphorus transporters and reduces serum phosphorus in open-label studies. A prospective, randomized, double-blind, placebo-controlled crossover trial was performed for assessment of the safety and efficacy of niacinamide. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Hemodialysis patients with phosphorus levels > or =5.0 mg/dl...
متن کاملLow Level of Autophagy-Related Gene 10 (ATG10) Expression in the 6-Hydroxydopamine Rat Model of Parkinson\'s Disease
Background: Autophagy is a mechanism disassembling the damaged organelles from the cell. This study attempted to examine the expression of several autophagy-related genes in Parkinson’s disease (PD) rat model. Methods: The male Wistar rats were divided into three groups as control, sham, and lesion. In the latter group, the PD rat model was induced by the injection of 6-hydroxydopamine in...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2020
ISSN: 0022-202X
DOI: 10.1016/j.jid.2020.03.254